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Jun Li, Ph.D.
Professor of Human GeneticsProfessor & Associate Chair for Research of Computational Medicine and BioinformaticsFaculty, Center for Statistical Genetics; Comprehensive Cancer CenterMember, Depression Center; Michigan Diabetes Research Center; Michigan Metabolomics & Obesity CenterCo-Director, Michigan Center for Single-Cell Genomic Data Analytics5940A Buhl1241 E. Catherine St. SPC 5618Ann Arbor, MI 48109-5618junzli@med.umich.edu734-615-5754
Courses
HG 544 - Basic Concepts in Population and Statistical Genetics
Fall term - 2 credits
Course Description:
The concepts and analytic methods for studying variation in human populations are the subject matter of this course. The topics covered include the distribution of genetic variation, major forces of genetic stasis and change, quantitative traits, linkage analysis, association tests, and the role of the environment. We take a problem solving approach and present the basic models of population, quantitative, and statistical genetics at a mathematical level appropriate to students in the life sciences. Our focus is on current human genetics research. However, most of what we present is broadly useful and applies to natural populations of other species.
Prerequisites:
A foundation in genetics and familiarity with the basic statistics and probability.
SyllabusHG544_2018_Aug28.pdf